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Embryonic Stem Cell Engineering with a Glycomimetic FGF2/BMP4 Co-Receptor Drives Mesodermal Differentiation in a Three-Dimensional Culture

Cell surface glycans, such as heparan sulfate (HS), are increasingly identified as co-regulators of growth factor signaling in early embryonic development; therefore, chemical tailoring of HS activity within the cellular glycocalyx of stem cells offers an opportunity to control their differentiation...

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發表在:ACS Chem Biol
Main Authors: Naticchia, Matthew R., Laubach, Logan K., Tota, Ember M., Lucas, Taryn M., Huang, Mia L., Godula, Kamil
格式: Artigo
語言:Inglês
出版: 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6252183/
https://ncbi.nlm.nih.gov/pubmed/30157624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00436
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