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Androgen receptor agonists increase lean mass, improve cardiopulmonary functions and extend survival in preclinical models of Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is a neuromuscular disease that predominantly affects boys as a result of mutation(s) in the dystrophin gene. DMD is characterized by musculoskeletal and cardiopulmonary complications, resulting in shorter life-span. Boys afflicted by DMD typically exhibit symptoms...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Ponnusamy, Suriyan, Sullivan, Ryan D., You, Dahui, Zafar, Nadeem, He Yang, Chuan, Thiyagarajan, Thirumagal, Johnson, Daniel L., Barrett, Maron L., Koehler, Nikki J., Star, Mayra, Stephenson, Erin J., Bridges, Dave, Cormier, Stephania A., Pfeffer, Lawrence M., Narayanan, Ramesh
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6251687/
https://ncbi.nlm.nih.gov/pubmed/28453658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddx150
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