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A homozygous mutation p.Arg2167Trp in FREM2 causes isolated cryptophthalmos

Cryptophthalmos (CO, MIM: 123570) is rare congenital anomalies of eyelid formation, which can occur alone or in combination with multiple congenital anomalies as part of Fraser syndrome (FS) or Manitoba Oculotrichoanal syndrome. Causal mutations have been identified for these syndromes but not in th...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Yu, Qian, Lin, Bingying, Xie, Shangqian, Gao, Song, Li, Wei, Liu, Yizhi, Wang, Hongwei, Huang, Danping, Xie, Zhi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6251612/
https://ncbi.nlm.nih.gov/pubmed/29688405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy144
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