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Codelivery of a cytotoxin and photosensitiser via a liposomal nanocarrier: a novel strategy for light-triggered cytosolic release

Endosomal entrapment is a key issue for the intracellular delivery of many nano-sized biotherapeutics to their cytosolic or nuclear targets. Photochemical internalisation (PCI) is a novel light-based solution that can be used to trigger the endosomal escape of a range of bioactive agents into the cy...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nanoscale
Hauptverfasser: Yaghini, Elnaz, Dondi, Ruggero, Edler, Karen J., Loizidou, Marilena, MacRobert, Alexander J., Eggleston, Ian M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Royal Society of Chemistry 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6251340/
https://ncbi.nlm.nih.gov/pubmed/30376028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8nr04048f
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