Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human Tuberculosis

Heme oxygenase-1 (HO-1) is a cytoprotective enzyme that controls inflammatory responses and redox homeostasis; however, its role during pulmonary tuberculosis (TB) remains unclear. Using freshly resected human TB lung tissue, we examined the role of HO-1 within the cellular and pathological spectrum...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Chinta, Krishna C., Rahman, Md. Aejazur, Saini, Vikram, Glasgow, Joel N., Reddy, Vineel P., Lever, Jeremie M., Nhamoyebonde, Shepherd, Leslie, Alasdair, Wells, Ryan M., Traylor, Amie, Madansein, Rajhmun, Siegal, Gene P., Antony, Veena B., Deshane, Jessy, Wells, Gordon, Nargan, Kievershen, George, James F., Ramdial, Pratistadevi K., Agarwal, Anupam, Steyn, Adrie J.C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Press 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6250977/
https://ncbi.nlm.nih.gov/pubmed/30428359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.10.073
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