Pressure-dependent NOS activation contributes to endothelial hyperpermeability in a model of acute heart failure

Aims: Acute increases in left ventricular end diastolic pressure (LVEDP) can induce pulmonary edema (PE). The mechanism(s) for this rapid onset edema may involve more than just increased fluid filtration. Lung endothelial cell permeability is regulated by pressure-dependent activation of nitric oxid...

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Dettagli Bibliografici
Pubblicato in:Biosci Rep
Autori principali: Chignalia, Andreia Z., Isbatan, Ayman, Patel, Milan, Ripper, Richard, Sharlin, Jordan, Shosfy, Joelle, Borlaug, Barry A., Dull, Randal O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2018
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6250809/
https://ncbi.nlm.nih.gov/pubmed/30355657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20181239
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