Pressure-dependent NOS activation contributes to endothelial hyperpermeability in a model of acute heart failure

Aims: Acute increases in left ventricular end diastolic pressure (LVEDP) can induce pulmonary edema (PE). The mechanism(s) for this rapid onset edema may involve more than just increased fluid filtration. Lung endothelial cell permeability is regulated by pressure-dependent activation of nitric oxid...

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Publicado en:Biosci Rep
Autores principales: Chignalia, Andreia Z., Isbatan, Ayman, Patel, Milan, Ripper, Richard, Sharlin, Jordan, Shosfy, Joelle, Borlaug, Barry A., Dull, Randal O.
Formato: Artigo
Lenguaje:Inglês
Publicado: Portland Press Ltd. 2018
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6250809/
https://ncbi.nlm.nih.gov/pubmed/30355657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20181239
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