Primary tumor-derived exosomes facilitate metastasis by regulating adhesion of circulating tumor cells via SMAD3 in liver cancer

Hepatocellular carcinoma (HCC) is a fatal disease and patients with HCC frequently die from metastasis. The mechanisms of HCC metastasis are not completely understood. In the present study, in vitro and in vivo data showed that HCC cells promoted cancer cell proliferation and lung metastases formati...

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Bibliografske podrobnosti
izdano v:Oncogene
Main Authors: Fu, Qihan, Zhang, Qi, Lou, Yu, Yang, Jiaqi, Nie, Gang, Chen, Qi, Chen, Yiwen, Zhang, Jingying, Wang, Jianxin, Wei, Tao, Qin, Hao, Dang, Xiaowei, Bai, Xueli, Liang, Tingbo
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6250679/
https://ncbi.nlm.nih.gov/pubmed/29991801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0391-0
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