Primary tumor-derived exosomes facilitate metastasis by regulating adhesion of circulating tumor cells via SMAD3 in liver cancer

Hepatocellular carcinoma (HCC) is a fatal disease and patients with HCC frequently die from metastasis. The mechanisms of HCC metastasis are not completely understood. In the present study, in vitro and in vivo data showed that HCC cells promoted cancer cell proliferation and lung metastases formati...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Fu, Qihan, Zhang, Qi, Lou, Yu, Yang, Jiaqi, Nie, Gang, Chen, Qi, Chen, Yiwen, Zhang, Jingying, Wang, Jianxin, Wei, Tao, Qin, Hao, Dang, Xiaowei, Bai, Xueli, Liang, Tingbo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6250679/
https://ncbi.nlm.nih.gov/pubmed/29991801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0391-0
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