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Withdrawal of Parathyroid hormone after prolonged administration leads to adipogenic differentiation of mesenchymal precursors in vivo
Intermittent PTH-like drugs are the only approved so-called anabolic agent that increases bone mass in both mice and humans. It is well documented that PTH targets mature cells of the osteoblast lineage, with only indirect evidence of its actions on early cells of the osteoblast lineage. Using a tri...
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| Vydáno v: | Bone |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6250592/ https://ncbi.nlm.nih.gov/pubmed/29800694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2018.05.024 |
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