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Loss of G(s)α Early in the Osteoblast Lineage Favors Adipogenic Differentiation of Mesenchymal Progenitors and Committed Osteoblast Precursors

In humans, aging and glucocorticoid treatment are associated with reduced bone mass and increased marrow adiposity, suggesting that the differentiation of osteoblasts and adipocytes may be coordinately regulated. Within the bone marrow, both osteoblasts and adipocytes are derived from mesenchymal pr...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Sinha, Partha, Aarnisalo, Piia, Chubb, Rhiannon, Ono, Noriaki, Fulzele, Keertik, Selig, Martin, Saeed, Hamid, Chen, Min, Weinstein, Lee S, Pajevic, Paola Divieti, Kronenberg, Henry M, Wu, Joy Y
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220542/
https://ncbi.nlm.nih.gov/pubmed/24806274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2270
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