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Loss of G(s)α Early in the Osteoblast Lineage Favors Adipogenic Differentiation of Mesenchymal Progenitors and Committed Osteoblast Precursors

In humans, aging and glucocorticoid treatment are associated with reduced bone mass and increased marrow adiposity, suggesting that the differentiation of osteoblasts and adipocytes may be coordinately regulated. Within the bone marrow, both osteoblasts and adipocytes are derived from mesenchymal pr...

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Bibliografiska uppgifter
I publikationen:J Bone Miner Res
Huvudupphovsmän: Sinha, Partha, Aarnisalo, Piia, Chubb, Rhiannon, Ono, Noriaki, Fulzele, Keertik, Selig, Martin, Saeed, Hamid, Chen, Min, Weinstein, Lee S, Pajevic, Paola Divieti, Kronenberg, Henry M, Wu, Joy Y
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220542/
https://ncbi.nlm.nih.gov/pubmed/24806274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2270
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