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Assessing the Causal Role of Body Mass Index on Cardiovascular Health in Young Adults: Mendelian Randomization and Recall-by-Genotype Analyses

BACKGROUND: Body mass index (BMI) has been suggested to be causally related to cardiovascular health in mid-to-late life, but this has not been explored systematically at younger ages—nor with detailed cardiovascular phenotyping. Recall-by-Genotype (RbG) is an approach that enables the collection of...

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Detalhes bibliográficos
Publicado no:Circulation
Main Authors: Wade, Kaitlin H., Chiesa, Scott T., Hughes, Alun D., Chaturvedi, Nish, Charakida, Marietta, Rapala, Alicja, Muthurangu, Vivek, Khan, Tauseef, Finer, Nicholas, Sattar, Naveed, Howe, Laura D., Fraser, Abigail, Lawlor, Debbie A., Davey Smith, George, Deanfield, John E., Timpson, Nicholas J.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6250296/
https://ncbi.nlm.nih.gov/pubmed/30524135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.117.033278
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