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Assessing the Causal Role of Body Mass Index on Cardiovascular Health in Young Adults: Mendelian Randomization and Recall-by-Genotype Analyses

BACKGROUND: Body mass index (BMI) has been suggested to be causally related to cardiovascular health in mid-to-late life, but this has not been explored systematically at younger ages—nor with detailed cardiovascular phenotyping. Recall-by-Genotype (RbG) is an approach that enables the collection of...

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Bibliographic Details
Published in:Circulation
Main Authors: Wade, Kaitlin H., Chiesa, Scott T., Hughes, Alun D., Chaturvedi, Nish, Charakida, Marietta, Rapala, Alicja, Muthurangu, Vivek, Khan, Tauseef, Finer, Nicholas, Sattar, Naveed, Howe, Laura D., Fraser, Abigail, Lawlor, Debbie A., Davey Smith, George, Deanfield, John E., Timpson, Nicholas J.
Format: Artigo
Language:Inglês
Published: Lippincott Williams & Wilkins 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6250296/
https://ncbi.nlm.nih.gov/pubmed/30524135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.117.033278
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