Assessing the Causal Role of Body Mass Index on Cardiovascular Health in Young Adults: Mendelian Randomization and Recall-by-Genotype Analyses

BACKGROUND: Body mass index (BMI) has been suggested to be causally related to cardiovascular health in mid-to-late life, but this has not been explored systematically at younger ages—nor with detailed cardiovascular phenotyping. Recall-by-Genotype (RbG) is an approach that enables the collection of...

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Veröffentlicht in:Circulation
Hauptverfasser: Wade, Kaitlin H., Chiesa, Scott T., Hughes, Alun D., Chaturvedi, Nish, Charakida, Marietta, Rapala, Alicja, Muthurangu, Vivek, Khan, Tauseef, Finer, Nicholas, Sattar, Naveed, Howe, Laura D., Fraser, Abigail, Lawlor, Debbie A., Davey Smith, George, Deanfield, John E., Timpson, Nicholas J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Lippincott Williams & Wilkins 2018
Schlagworte:
Original Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6250296/
https://ncbi.nlm.nih.gov/pubmed/30524135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.117.033278
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