Regulation of MRTF-A by JMY via a nucleation-independent mechanism

BACKGROUND: MRTF-A (myocardin-related transcription factor A) is a coactivator for SRF-mediated gene expression. The activity of MRTF-A is critically dependent on the dissociation of G-actin from N-terminal RPEL motifs. MRTF-SRF induction often correlates with enhanced polymerization of F-actin. Her...

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Bibliographic Details
Published in:Cell Commun Signal
Main Authors: Kluge, Franziska, Weissbach, Julia, Weber, Anja, Stradal, Theresia, Posern, Guido
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249979/
https://ncbi.nlm.nih.gov/pubmed/30463620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-018-0299-x
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