Tightly controlled MRTF-A activity regulates epithelial differentiation during formation of mammary acini

BACKGROUND: Myocardin-related transcription factors (MRTF) A and B link actin dynamics and mechanotransduction to gene expression. In mice, MRTF-A is involved in mammary gland differentiation, but its role in human mammary epithelial cells remains unclear. METHODS: Three-dimensional cultures of huma...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Breast Cancer Res
Prif Awduron: Seifert, Anja, Posern, Guido
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2017
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5463372/
https://ncbi.nlm.nih.gov/pubmed/28592291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-017-0860-3
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