Pathogenicity of Ebola and Marburg Viruses Is Associated With Differential Activation of the Myeloid Compartment in Humanized Triple Knockout-Bone Marrow, Liver, and Thymus Mice

Ebola virus (EBOV) and Marburg virus (MARV) outbreaks are highly lethal, and infection results in a hemorrhagic fever with complex etiology. These zoonotic viruses dysregulate the immune system to cause disease, in part by replicating within myeloid cells that would normally innately control viral i...

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Publicado en:J Infect Dis
Autores principales: Lavender, Kerry J, Williamson, Brandi N, Saturday, Greg, Martellaro, Cynthia, Griffin, Amanda, Hasenkrug, Kim J, Feldmann, Heinz, Prescott, Joseph
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
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Supplement Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249575/
https://ncbi.nlm.nih.gov/pubmed/30085162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy269
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