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Improving SNP prioritization and pleiotropic architecture estimation by incorporating prior knowledge using graph-GPA
SUMMARY: Integration of genetic studies for multiple phenotypes is a powerful approach to improving the identification of genetic variants associated with complex traits. Although it has been shown that leveraging shared genetic basis among phenotypes, namely pleiotropy, can increase statistical pow...
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| Publicado en: | Bioinformatics |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6248798/ https://ncbi.nlm.nih.gov/pubmed/29432514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty061 |
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