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Reverse Transduction Can Improve Efficiency of AAV Vectors in Transduction-Resistant Cells

Reverse transduction, also known as substrate-mediated gene delivery, is a strategy in which viral vectors are first coated onto a surface that subsequently comes into contact with mammalian cells. The cells internalize the surface-attached vectors, resulting in transgene expression. We hypothesized...

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Bibliografiske detaljer
Udgivet i:Biotechnol Bioeng
Main Authors: Lee, Esther J., Robinson, Tawana M., Tabor, Jeffrey J., Mikos, Antonios G., Suh, Junghae
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6248337/
https://ncbi.nlm.nih.gov/pubmed/30199099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26830
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