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Influence of particle size and shape on their margination and wall-adhesion: Implications in drug delivery vehicle design across nano-to-micro scale

Intravascular drug delivery technologies majorly utilize spherical nanoparticles as carrier vehicles. Their targets are often at the blood vessel wall or in the tissue beyond the wall, such that vehicle localization towards the wall (margination) becomes a pre-requisite for their function. To this e...

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Bibliographische Detailangaben
Veröffentlicht in:Nanoscale
Hauptverfasser: Cooley, Michaela, Sarode, Apoorva, Hoore, Masoud, Fedosov, Dmitry A., Mitragotri, Samir, Gupta, Anirban Sen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6247903/
https://ncbi.nlm.nih.gov/pubmed/30080212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8nr04042g
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