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Shape Induced Inhibition of Phagocytosis of Polymer Particles

PURPOSE: To determine if particle shape can be engineered to inhibit phagocytosis of drug delivery particles by macrophages, which can be a significant barrier to successful therapeutic delivery. METHODS: Non-spherical polystyrene particles were fabricated by stretching spherical particles embedded...

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Detalhes bibliográficos
Main Authors: Champion, Julie A., Mitragotri, Samir
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810499/
https://ncbi.nlm.nih.gov/pubmed/18548338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-008-9626-z
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