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Klotho Ameliorates Medullary Fibrosis and Pressure Natriuresis in Hypertensive Rat Kidneys

Renal expression of klotho is reduced in hypertension. Experiments were performed to examine whether exogenous klotho protein supplementation ameliorates pressure natriuresis in early phase of hypertension, using stroke-prone spontaneously hypertensive rats (sp-SHR). The interactions between klotho...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Takenaka, Tsuneo, Inoue, Tsutomu, Miyazaki, Takashi, Kobori, Hiroyuki, Nishiyama, Akira, Ishii, Naohito, Hayashi, Matsuhiko, Suzuki, Hiromichi
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6247804/
https://ncbi.nlm.nih.gov/pubmed/30354813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.118.11176
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