Klotho Ameliorates Medullary Fibrosis and Pressure Natriuresis in Hypertensive Rat Kidneys

Renal expression of klotho is reduced in hypertension. Experiments were performed to examine whether exogenous klotho protein supplementation ameliorates pressure natriuresis in early phase of hypertension, using stroke-prone spontaneously hypertensive rats (sp-SHR). The interactions between klotho...

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Bibliografiset tiedot
Julkaisussa:Hypertension
Päätekijät: Takenaka, Tsuneo, Inoue, Tsutomu, Miyazaki, Takashi, Kobori, Hiroyuki, Nishiyama, Akira, Ishii, Naohito, Hayashi, Matsuhiko, Suzuki, Hiromichi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6247804/
https://ncbi.nlm.nih.gov/pubmed/30354813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.118.11176
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