Fibroblast Expression of an IκB Dominant-Negative Transgene Attenuates Renal Fibrosis

It is not clear whether interstitial fibroblasts or tubular epithelial cells are primarily responsible for the profibrotic effects of NF-κB activation during renal fibrogenesis. Here, we crossed mice carrying a conditional IκB dominant-negative transgene (IκBdN) with mice transgenic for cell-specifi...

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Bibliografische gegevens
Hoofdauteurs: Inoue, Tsutomu, Takenaka, Tsuneo, Hayashi, Matsuhiko, Monkawa, Toshiaki, Yoshino, Jun, Shimoda, Kouji, Neilson, Eric G., Suzuki, Hiromichi, Okada, Hirokazu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Nephrology 2010
Onderwerpen:
Brief Communications
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014017/
https://ncbi.nlm.nih.gov/pubmed/20847140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010010003
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