Cleavage of the extracellular domain of junctional adhesion molecule-A is associated with resistance to anti-HER2 therapies in breast cancer settings

BACKGROUND: Junctional adhesion molecule-A (JAM-A) is an adhesion molecule whose overexpression on breast tumor tissue has been associated with aggressive cancer phenotypes, including human epidermal growth factor receptor-2 (HER2)-positive disease. Since JAM-A has been described to regulate HER2 ex...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Breast Cancer Res
Main Authors: Leech, Astrid O., Vellanki, Sri HariKrishna, Rutherford, Emily J., Keogh, Aoife, Jahns, Hanne, Hudson, Lance, O’Donovan, Norma, Sabri, Siham, Abdulkarim, Bassam, Sheehan, Katherine M., Kay, Elaine W., Young, Leonie S., Hill, Arnold D. K., Smith, Yvonne E., Hopkins, Ann M.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6247757/
https://ncbi.nlm.nih.gov/pubmed/30458861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-018-1064-1
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki