MUC1 deficiency mediates corticosteroid resistance in chronic obstructive pulmonary disease

BACKGROUND: Lung inflammation in COPD is poorly controlled by inhaled corticosteroids (ICS). Strategies to improve ICS efficacy or the search of biomarkers who may select those patients candidates to receive ICS in COPD are needed. Recent data indicate that MUC1 cytoplasmic tail (CT) membrane mucin...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Milara, Javier, Díaz-Platas, Lucía, Contreras, Sonia, Ribera, Pilar, Roger, Inés, Ballester, Beatriz, Montero, Paula, Cogolludo, Ángel, Morcillo, Esteban, Cortijo, Julio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6247701/
https://ncbi.nlm.nih.gov/pubmed/30458870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-018-0927-4
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