MUC1 deficiency mediates corticosteroid resistance in chronic obstructive pulmonary disease

Abstract Background Lung inflammation in COPD is poorly controlled by inhaled corticosteroids (ICS). Strategies to improve ICS efficacy or the search of biomarkers who may select those patients candidates to receive ICS in COPD are needed. Recent data indicate that MUC1 cytoplasmic tail (CT) membran...

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Detalhes bibliográficos
Main Authors: Javier Milara, Lucía Díaz-Platas, Sonia Contreras, Pilar Ribera, Inés Roger, Beatriz Ballester, Paula Montero, Ángel Cogolludo, Esteban Morcillo, Julio Cortijo
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2018-11-01
Colecção:Respiratory Research
Assuntos:
Chronic obstructive pulmonary disease
MUC1
Corticosteroid resistance
Acesso em linha:http://link.springer.com/article/10.1186/s12931-018-0927-4
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