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Runx2-mediated activation of the Bax gene increases osteosarcoma cell sensitivity to apoptosis
The Runx family of transcription factors regulate cell growth and differentiation, and control the expression of target genes involved in cell fate decisions. We examined the role of the bone-related member of this family, Runx2, in regulating apoptosis via modulation of the Bcl2 family of genes in...
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| Veröffentlicht in: | Oncogene |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6247425/ https://ncbi.nlm.nih.gov/pubmed/18223689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1211020 |
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