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Osteogenic protein-1 inhibits nucleus pulposus cell apoptosis through regulating the NF-κB/ROS pathway in an inflammation environment

Background: Intervertebral disc degeneration is a pathological process that involves an inflammation response. As a classical cellular feature, several studies have demonstrated that inflammation can promote nucleus pulposus (NP) cell apoptosis. Therefore, attenuation of NP cell apoptosis may be a p...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Yu, Wei, Fu, Jiabin, Liu, Yan, Wu, Yuchi, Jiang, Dianming
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6246766/
https://ncbi.nlm.nih.gov/pubmed/30341245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20181530
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