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Molecular simulation and in vitro evaluation of chitosan nanoparticles as drug delivery systems for the controlled release of anticancer drug cytarabine against solid tumours

The present work is an attempt to integrate the molecular simulation studies with in vitro cytotoxicity of cytarabine-loaded chitosan nanoparticles and exploring the potential of this formulation as therapeutics for treating solid tumours. The molecular simulation was performed using GROMACS v5.4 in...

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Detalhes bibliográficos
Publicado no:3 Biotech
Main Authors: Deepa, G., Sivakumar, K. C., Sajeevan, T. P.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6246757/
https://ncbi.nlm.nih.gov/pubmed/30498666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13205-018-1510-x
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