Silencing SOCS3 Markedly Deteriorates Spondyloarthritis in Mice Induced by Minicircle DNA Expressing IL23

Objective: Despite extensive studies, the precise mechanism underlying spondyloarthritis, especially ankylosing spondylitis, remains elusive. This study aimed to develop an ideal animal model for an insight into mechanism of spondyloarthritis and functional relevance of SOCS3 in spondyloarthritis. M...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Chen, Yuhai, Ouyang, Jing, Yan, Ruoxiang, Maarouf, Mohamed Hassan, Wang, Xuefei, Chen, Biao, Liu, Shasha, Hu, Jiayue, Guo, Guijie, Zhang, Jing, Dai, Sheng-Ming, Xu, Huji, Chen, Ji-Long
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6246747/
https://ncbi.nlm.nih.gov/pubmed/30487798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02641
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