(+)-JQ1 attenuated LPS-induced microglial inflammation via MAPK/NFκB signaling

BACKGROUND: Microglia activation is a crucial event in neurodegenerative disease. The depression of microglial inflammatory response is considered a promising therapeutic strategy. NFκB signaling, including IKK/IκB phosphotylation, p65 nucelus relocalization and NFκB-related genes transcription are...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Biosci
Main Authors: Wang, Huanhuan, Huang, Wenhai, Liang, Meihao, Shi, Yingying, Zhang, Chixiao, Li, Qin, Liu, Meng, Shou, Yikai, Yin, Hongping, Zhu, Xiaozheng, Sun, Xiaoyan, Hu, Yu, Shen, Zhengrong
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6245926/
https://ncbi.nlm.nih.gov/pubmed/30479742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-018-0258-7
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