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(+)-JQ1 attenuated LPS-induced microglial inflammation via MAPK/NFκB signaling
BACKGROUND: Microglia activation is a crucial event in neurodegenerative disease. The depression of microglial inflammatory response is considered a promising therapeutic strategy. NFκB signaling, including IKK/IκB phosphotylation, p65 nucelus relocalization and NFκB-related genes transcription are...
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| Izdano u: | Cell Biosci |
|---|---|
| Glavni autori: | , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6245926/ https://ncbi.nlm.nih.gov/pubmed/30479742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-018-0258-7 |
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