Aspirin-triggered lipoxin A(4 )attenuates LPS-induced pro-inflammatory responses by inhibiting activation of NF-κB and MAPKs in BV-2 microglial cells

BACKGROUND: Microglial activation plays an important role in neurodegenerative diseases through production of nitric oxide (NO) and several pro-inflammatory cytokines. Lipoxins (LXs) and aspirin-triggered LXs (ATLs) are considered to act as 'braking signals' in inflammation. In the present...

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Detalhes bibliográficos
Main Authors: Wang, Yan-Ping, Wu, Yan, Li, Long-Yan, Zheng, Jin, Liu, Ren-Gang, Zhou, Jie-Ping, Yuan, Shi-Ying, Shang, You, Yao, Shang-Long
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162900/
https://ncbi.nlm.nih.gov/pubmed/21831303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-95
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