A novel non-sulphamoylated 2-methoxyestradiol derivative causes detachment of breast cancer cells by rapid disassembly of focal adhesions

BACKGROUND: 2-Methoxyestradiol (2ME2) is an estradiol metabolite with well documented antiproliferative properties in many cancer cell lines. However, it is rapidly metabolised in vivo which limits its clinical application. Therefore, more stable derivatives with potentially improved clinical featur...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Botes, Mandie, Jurgens, Tamarin, Riahi, Zohreh, Visagie, Michelle, Janse van Vuuren, Rustelle, Joubert, Anna Margaretha, van den Bout, Iman
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6245879/
https://ncbi.nlm.nih.gov/pubmed/30479567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-018-0688-7
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados