Loss of DNA methylation is related to increased expression of miR-21 and miR-146b in papillary thyroid carcinoma

BACKGROUND: DNA methylation in miRNA genes has been reported as a mechanism that may cause dysregulation of mature miRNAs and consequently impact the gene expression. This mechanism is largely unstudied in papillary thyroid carcinomas (PTC). METHODS: To identify differentially methylated miRNA-encod...

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Gepubliceerd in:Clin Epigenetics
Hoofdauteurs: Ortiz, Isabella Maria Dias Payão, Barros-Filho, Mateus Camargo, dos Reis, Mariana Bisarro, Beltrami, Caroline Moraes, Marchi, Fabio Albuquerque, Kuasne, Hellen, do Canto, Luísa Matos, de Mello, Julia Bette Homem, Abildgaard, Cecilie, Pinto, Clóvis Antônio Lopes, Kowalski, Luiz Paulo, Rogatto, Silvia Regina
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2018
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6245861/
https://ncbi.nlm.nih.gov/pubmed/30454026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0579-8
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