Loss of DNA methylation is related to increased expression of miR-21 and miR-146b in papillary thyroid carcinoma

BACKGROUND: DNA methylation in miRNA genes has been reported as a mechanism that may cause dysregulation of mature miRNAs and consequently impact the gene expression. This mechanism is largely unstudied in papillary thyroid carcinomas (PTC). METHODS: To identify differentially methylated miRNA-encod...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Ortiz, Isabella Maria Dias Payão, Barros-Filho, Mateus Camargo, dos Reis, Mariana Bisarro, Beltrami, Caroline Moraes, Marchi, Fabio Albuquerque, Kuasne, Hellen, do Canto, Luísa Matos, de Mello, Julia Bette Homem, Abildgaard, Cecilie, Pinto, Clóvis Antônio Lopes, Kowalski, Luiz Paulo, Rogatto, Silvia Regina
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6245861/
https://ncbi.nlm.nih.gov/pubmed/30454026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0579-8
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