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Saccharomyces cerevisiae adapted to grow in the presence of low-dose rapamycin exhibit altered amino acid metabolism

BACKGROUND: Rapamycin is a potent inhibitor of the highly conserved TOR kinase, the nutrient-sensitive controller of growth and aging. It has been utilised as a chemotherapeutic agent due to its anti-proliferative properties and as an immunosuppressive drug, and is also known to extend lifespan in a...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Cell Commun Signal
Κύριοι συγγραφείς: Dikicioglu, Duygu, Dereli Eke, Elif, Eraslan, Serpil, Oliver, Stephen G., Kirdar, Betul
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: BioMed Central 2018
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6245637/
https://ncbi.nlm.nih.gov/pubmed/30458881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-018-0298-y
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