Saccharomyces cerevisiae adapted to grow in the presence of low-dose rapamycin exhibit altered amino acid metabolism

BACKGROUND: Rapamycin is a potent inhibitor of the highly conserved TOR kinase, the nutrient-sensitive controller of growth and aging. It has been utilised as a chemotherapeutic agent due to its anti-proliferative properties and as an immunosuppressive drug, and is also known to extend lifespan in a...

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Bibliografiska uppgifter
I publikationen:Cell Commun Signal
Huvudupphovsmän: Dikicioglu, Duygu, Dereli Eke, Elif, Eraslan, Serpil, Oliver, Stephen G., Kirdar, Betul
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2018
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6245637/
https://ncbi.nlm.nih.gov/pubmed/30458881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-018-0298-y
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