Insulin-like growth factor receptor signaling in breast tumor epithelium protects cells from endoplasmic reticulum stress and regulates the tumor microenvironment

BACKGROUND: Early analyses of human breast cancer identified high expression of the insulin-like growth factor type 1 receptor (IGF-1R) correlated with hormone receptor positive breast cancer and associated with a favorable prognosis, whereas low expression of IGF-1R correlated with triple negative...

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Publicado en:Breast Cancer Res
Main Authors: Obr, Alison E., Kumar, Sushil, Chang, Yun-Juan, Bulatowicz, Joseph J., Barnes, Betsy J., Birge, Raymond B., Lazzarino, Deborah A., Gallagher, Emily, LeRoith, Derek, Wood, Teresa L.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2018
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6245538/
https://ncbi.nlm.nih.gov/pubmed/30458886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-018-1063-2
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