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Design, Synthesis and Applications of Hyaluronic Acid-Paclitaxel Bioconjugates†

Paclitaxel (1a), a well known antitumor agent adopted mainly for the treatment of breast and ovarian cancer, suffers from significant disadvantages such as low solubility, certain toxicity and specific drug-resistance of some tumor cells. To overcome these problems extensive research has been carrie...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Leonelli, Francesca, La Bella, Angela, Migneco, Luisa Maria, Bettolo, Rinaldo Marini
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6245481/
https://ncbi.nlm.nih.gov/pubmed/18305424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules13020360
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