miR-30a Remodels Subcutaneous Adipose Tissue Inflammation to Improve Insulin Sensitivity in Obesity

Chronic inflammation accompanies obesity and limits subcutaneous white adipose tissue (WAT) expandability, accelerating the development of insulin resistance and type 2 diabetes mellitus. MicroRNAs (miRNAs) influence expression of many metabolic genes in fat cells, but physiological roles in WAT rem...

Full description

Saved in:
Bibliographic Details
Published in:Diabetes
Main Authors: Koh, Eun-Hee, Chernis, Natasha, Saha, Pradip K., Xiao, Liuling, Bader, David A., Zhu, Bokai, Rajapakshe, Kimal, Hamilton, Mark P., Liu, Xia, Perera, Dimuthu, Chen, Xi, York, Brian, Trauner, Michael, Coarfa, Cristian, Bajaj, Mandeep, Moore, David D., Deng, Tuo, McGuire, Sean E., Hartig, Sean M.
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2018
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6245225/
https://ncbi.nlm.nih.gov/pubmed/30002134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db17-1378
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items