miR-30a Remodels Subcutaneous Adipose Tissue Inflammation to Improve Insulin Sensitivity in Obesity

Chronic inflammation accompanies obesity and limits subcutaneous white adipose tissue (WAT) expandability, accelerating the development of insulin resistance and type 2 diabetes mellitus. MicroRNAs (miRNAs) influence expression of many metabolic genes in fat cells, but physiological roles in WAT rem...

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Bibliografske podrobnosti
izdano v:Diabetes
Main Authors: Koh, Eun-Hee, Chernis, Natasha, Saha, Pradip K., Xiao, Liuling, Bader, David A., Zhu, Bokai, Rajapakshe, Kimal, Hamilton, Mark P., Liu, Xia, Perera, Dimuthu, Chen, Xi, York, Brian, Trauner, Michael, Coarfa, Cristian, Bajaj, Mandeep, Moore, David D., Deng, Tuo, McGuire, Sean E., Hartig, Sean M.
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2018
Teme:
Signal Transduction
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6245225/
https://ncbi.nlm.nih.gov/pubmed/30002134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db17-1378
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