Transcription Factor 7-Like 2 (TCF7L2) Gene Polymorphism and Progression From Single to Multiple Autoantibody Positivity in Individuals at Risk for Type 1 Diabetes

OBJECTIVE: The type 2 diabetes–associated alleles at the TCF7L2 locus mark a type 1 diabetes phenotype characterized by single islet autoantibody positivity as well as lower glucose and higher C-peptide measures. Here, we studied whether the TCF7L2 locus influences progression of islet autoimmunity,...

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Bibliografske podrobnosti
izdano v:Diabetes Care
Main Authors: Redondo, Maria J., Steck, Andrea K., Sosenko, Jay, Anderson, Mark, Antinozzi, Peter, Michels, Aaron, Wentworth, John M., Atkinson, Mark A., Pugliese, Alberto, Geyer, Susan
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2018
Teme:
Epidemiology/Health Services Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6245213/
https://ncbi.nlm.nih.gov/pubmed/30275285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc18-0861
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