A Type 1 Diabetes Genetic Risk Score Predicts Progression of Islet Autoimmunity and Development of Type 1 Diabetes in Individuals at Risk

OBJECTIVE: We tested the ability of a type 1 diabetes (T1D) genetic risk score (GRS) to predict progression of islet autoimmunity and T1D in at-risk individuals. RESEARCH DESIGN AND METHODS: We studied the 1,244 TrialNet Pathway to Prevention study participants (T1D patients’ relatives without diabe...

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Detalhes bibliográficos
Publicado no:Diabetes Care
Main Authors: Redondo, Maria J., Geyer, Susan, Steck, Andrea K., Sharp, Seth, Wentworth, John M., Weedon, Michael N., Antinozzi, Peter, Sosenko, Jay, Atkinson, Mark, Pugliese, Alberto, Oram, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2018
Assuntos:
Epidemiology/Health Services Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105323/
https://ncbi.nlm.nih.gov/pubmed/30002199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc18-0087
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