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Annexin A1-suppressed autophagy promotes nasopharyngeal carcinoma cell invasion and metastasis by PI3K/AKT signaling activation

Annexin A1 (ANXA1) is dysregulated in the various tumors. However, the role and mechanism of ANXA1 in the cancers are poorly understood. In this study, we first showed a clinically positive correlation between ANXA1 and autophagy-associated protein SQSTM1 expression in nasopharyngeal carcinoma (NPC)...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Zhu, Jin-Feng, Huang, Wei, Yi, Hong-Mei, Xiao, Ta, Li, Jiao-Yang, Feng, Juan, Yi, Hong, Lu, Shan-Shan, Li, Xin-Hui, Lu, Rou-Huang, He, Qiu-Yan, Xiao, Zhi-Qiang
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6244011/
https://ncbi.nlm.nih.gov/pubmed/30459351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1204-7
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