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Reduced RKIP enhances nasopharyngeal carcinoma radioresistance by increasing ERK and AKT activity

Raf kinase inhibitory protein (RKIP) functions as a chemo-immunotherapeutic sensitizer of cancers, but regulation of RKIP on tumor radiosensitivity remains largely unexplored. In this study, we investigate the role and mechanism of RKIP in nasopharyngeal carcinoma (NPC) radioresistance. The results...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Yuan, Li, Yi, Hong-Mei, Yi, Hong, Qu, Jia-Quan, Zhu, Jin-Feng, Li, Li-Na, Xiao, Ta, Zheng, Zhen, Lu, Shan-Shan, Xiao, Zhi-Qiang
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905486/
https://ncbi.nlm.nih.gov/pubmed/26862850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7201
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