Reduced RKIP enhances nasopharyngeal carcinoma radioresistance by increasing ERK and AKT activity

Raf kinase inhibitory protein (RKIP) functions as a chemo-immunotherapeutic sensitizer of cancers, but regulation of RKIP on tumor radiosensitivity remains largely unexplored. In this study, we investigate the role and mechanism of RKIP in nasopharyngeal carcinoma (NPC) radioresistance. The results...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yuan, Li, Yi, Hong-Mei, Yi, Hong, Qu, Jia-Quan, Zhu, Jin-Feng, Li, Li-Na, Xiao, Ta, Zheng, Zhen, Lu, Shan-Shan, Xiao, Zhi-Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905486/
https://ncbi.nlm.nih.gov/pubmed/26862850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7201
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