IL-15 enhanced antibody-dependent cellular cytotoxicity mediated by NK cells and macrophages

The goal of cancer immunotherapy is to stimulate the host immune system to attack malignant cells. Antibody-dependent cellular cytotoxicity (ADCC) is a pivotal mechanism of antitumor action of clinically employed antitumor antibodies. IL-15 administered to patients with metastatic malignancy by cont...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Zhang, Meili, Wen, Bernard, Anton, Olga M., Yao, Zhengsheng, Dubois, Sigrid, Ju, Wei, Sato, Noriko, DiLillo, David J., Bamford, Richard N., Ravetch, Jeffrey V., Waldmann, Thomas A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2018
Soggetti:
PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6243244/
https://ncbi.nlm.nih.gov/pubmed/30373815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1811615115
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