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Decreased BDNF Release in Cortical Neurons of a Knock-in Mouse Model of Huntington’s Disease
Huntington’s disease (HD) is a dominantly inherited neurodegenerative disease caused by an increase in CAG repeats in the Huntingtin gene (HTT). The striatum is one of the most vulnerable brain regions in HD, and altered delivery of BDNF to the striatum is believed to underlie this high vulnerabilit...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6242964/ https://ncbi.nlm.nih.gov/pubmed/30451892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34883-w |
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