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Contribution of p62/SQSTM1 to PDGF-BB-induced myofibroblast-like phenotypic transition in vascular smooth muscle cells lacking Smpd1 gene

Accumulating evidence indicates a critical role of autophagy in regulating vascular smooth muscle cell (SMC) homeostasis in atherogenesis. However, little is known about the modulatory role of autophagy in PDGF-BB-induced SMC transition towards the synthetic phenotype and extracellular matrix remode...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Dis
Hauptverfasser: Zhang, Peng, Guan, Yinglu, Chen, Jiajie, Li, Xiang, McConnell, Bradley K., Zhou, Wei, Boini, Krishna M., Zhang, Yang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6242941/
https://ncbi.nlm.nih.gov/pubmed/30451833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1197-2
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