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Sumoylation of RORγt regulates T(H)17 differentiation and thymocyte development
RORγt controls the differentiation of T(H)17 cells, which are mediators of autoimmune conditions such as experimental autoimmune encephalomyelitis (EAE). RORγt also regulates thymocyte development and lymph node genesis. Here we show that the function of RORγt is regulated by its sumoylation. Loss o...
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| Vydáno v: | Nat Commun |
|---|---|
| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6242824/ https://ncbi.nlm.nih.gov/pubmed/30451821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07203-z |
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