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Synthesis of the hexacyclic triterpene core of the jujuboside saponins via tandem Wolff rearrangement–intramolecular ketene hetero-Diels–Alder reaction()

The jujubosides are saponin natural products reported to have immunoadjuvant, anticancer, antibacterial, antifungal, and antisweet activities. The triterpene component, jujubogenin contains a unique tricyclic ketal motif comprising the DEF ring system. Herein, we describe our efforts toward the tota...

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Dades bibliogràfiques
Publicat a:Tetrahedron
Autors principals: Karimov, Rashad R., Tan, Derek S., Gin, David Y.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6242285/
https://ncbi.nlm.nih.gov/pubmed/30467444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2018.04.051
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