Mutation analysis of cell-free DNA and single circulating tumor cells in metastatic breast cancer patients with high CTC counts

PURPOSE: The purpose of this study was to directly compare mutation profiles in multiple single CTCs and cfDNA isolated from the same blood samples taken from patients with metastaic breast cancer (MBC). We aimed to determine whether cell-free DNA would reflect the heterogeneity observed in 40 singl...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Shaw, Jacqueline A., Guttery, David S., Hills, Allison, Fernandez-Garcia, Daniel, Page, Karen, Rosales, Brenda M., Goddard, Kate S., Hastings, Robert K., Luo, Jinli, Ogle, Olivia, Woodley, Laura, Ali, Simak, Stebbing, Justin, Coombes, R. Charles
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6241844/
https://ncbi.nlm.nih.gov/pubmed/27334837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-0825
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