Mutation analysis of cell-free DNA and single circulating tumor cells in metastatic breast cancer patients with high CTC counts

PURPOSE: The purpose of this study was to directly compare mutation profiles in multiple single CTCs and cfDNA isolated from the same blood samples taken from patients with metastaic breast cancer (MBC). We aimed to determine whether cell-free DNA would reflect the heterogeneity observed in 40 singl...

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Bibliografiset tiedot
Julkaisussa:Clin Cancer Res
Päätekijät: Shaw, Jacqueline A., Guttery, David S., Hills, Allison, Fernandez-Garcia, Daniel, Page, Karen, Rosales, Brenda M., Goddard, Kate S., Hastings, Robert K., Luo, Jinli, Ogle, Olivia, Woodley, Laura, Ali, Simak, Stebbing, Justin, Coombes, R. Charles
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6241844/
https://ncbi.nlm.nih.gov/pubmed/27334837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-0825
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