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Site-Specific Insulin-Trehalose Glycopolymer Conjugate by Grafting From Strategy Improves Bioactivity
Insulin is an important therapeutic protein for the treatment of diabetes, but it is unstable and aggregates upon exposure to environmental stressors encountered during storage and transport. To prevent degradation of the protein in this manner and retain as much in vivo bioactivity as possible, a w...
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| Pubblicato in: | ACS Macro Lett |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6241536/ https://ncbi.nlm.nih.gov/pubmed/30467526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmacrolett.7b00974 |
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