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Site-Specific Insulin-Trehalose Glycopolymer Conjugate by Grafting From Strategy Improves Bioactivity

Insulin is an important therapeutic protein for the treatment of diabetes, but it is unstable and aggregates upon exposure to environmental stressors encountered during storage and transport. To prevent degradation of the protein in this manner and retain as much in vivo bioactivity as possible, a w...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:ACS Macro Lett
मुख्य लेखकों: Mansfield, Kathryn M., Maynard, Heather D.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2018
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6241536/
https://ncbi.nlm.nih.gov/pubmed/30467526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmacrolett.7b00974
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